The Prime difference
Why Prime is different:
Serving communities, not Wall Street
Prime Therapeutics (Prime) is a pharmacy benefit manager collectively owned by not-for-profit Blue Cross and Blue Shield Plans, subsidiaries or affiliates of those plans — not outside shareholders. Prime’s incentives are aligned with community-based health plans and patient outcomes rather than Wall Street or outside investors.
That means our focus remains on helping health plans and employers manage costs while supporting patient access to affordable and effective care.
Prime in Florida
6M
Prime serves approximately 6 million Floridians.
2M
2 million Floridians get pharmacy benefits through a health plan, employer or other plan sponsor served by Prime.
3.6M
More than 3.6 million Floridians are supported through Medicare, Medicaid and other public health programs.
46
Prime provides pharmacy benefit services for 46 Florida employers, unions, school districts and other organizations across the state.
30+
Prime employs pharmacists, nurses and care specialists at our specialty pharmacy operations center in Orlando, which supports patients across 30+ specialty disease state categories.
How Prime improves patient care and affordability for Floridians
Combining clinical support with benefit design to improve health outcomes
Investing in innovative solutions that improve patient care and access
Addressing high-cost therapies with affordability solutions
Making pharmacy care easier to navigate
Clinical support that drives better outcomes
Prime connects care management and integrated benefit design to foster care coordination, improve outcomes and lower healthcare costs. For example, Prime’s KeepWell™ care management solution has proven instrumental in driving stronger medication adherence, lower overall costs and meaningful weight loss results for enrolled patients on glucagon-like peptide-1 receptor agonist (GLP-1) therapies.
21%
GLP-1 weight management costs for KeepWell participants are 21% lower compared to those not engaged in a care management program.
79%
79% of GLP-1 initiators were adherent to therapy, a 23 percentage-point improvement over those not in a care management program.
Innovative solutions that improve patient care and access
Prime’s innovative platforms help patients, providers and plan sponsors navigate care more effectively, bringing together clinical expertise, data and coordinated support.
Judi® integrates benefit information, clinical programs and digital tools in one coordinated experience, helping patients, providers and plan sponsors move from insight to action more easily.
HighTouchRx® is a clinical intervention program that uses Prime pharmacist expertise, advanced analytics and integrated medical and pharmacy data to identify patient-level savings opportunities for people on complex therapies.
IntegratedRx® connects patients with cancer or cystic fibrosis to specialty medication support through their health systems and clinics, bringing pharmacists closer to the care team to improve coordination, access and affordability.
Affordability solutions for high-cost therapies
Prime offers a suite of affordability solutions to address some of the biggest cost challenges in healthcare — especially for complex, high-cost therapies.
HighTouchRx® has contributed to more than $200 million in savings across commercial and Medicare plans since 2022.
IntegratedRx® has delivered more than $150 million in savings for health plans and clients, while also reducing total medical cost of care for oncology patients.
Advocate+™ Pharmacy Match helps patients starting specialty therapy find the right pharmacies and lowest-cost options and provides personalized support throughout their healthcare journeys.
Prime programs like Advocate+™ Pharmacy Match help generate millions of dollars in monthly savings for Florida’s largest health plan and its patients.
This solution matches members with specialty pharmacies that best meet their needs at the lowest available price — along with ongoing clinical support.
Pharmacy care that’s easier to navigate
Prime helps make pharmacy care simpler, more affordable and easier to navigate for Floridians across health plan, employer-sponsored, Medicare, Medicaid and public program coverage. From benefit support and specialized clinical care to home delivery, 24/7 access to healthcare experts, online refill tools and copay assistance, Prime helps patients understand their options, stay connected to care and get the support they need throughout their pharmacy journey.
Protecting Florida from fraud, waste and abuse
In 2025, Prime's Fraud, Waste and Abuse (FWA) program generated approximately $57 million in value for Florida-based clients while protecting members from unsafe and inappropriate pharmacy practices.
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